nounIntermediate
Definition
Synthetic 15-amino-acid peptide (body protection compound) derived from a protein in human gastric juice; studied for tissue repair, gut healing, and anti-inflammatory effects in preclinical models.
Detailed Explanation
BPC-157 (sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) has shown activity in animal models for tendon healing, ligament repair, gut protection (NSAIDs, alcohol damage), and wound healing. It appears to upregulate growth factor expression (VEGF, FGF) and modulate the nitric oxide system. Despite extensive preclinical literature, no completed human randomized controlled trials exist as of 2026, and its regulatory status varies by jurisdiction.
Key Facts
- BPC-157 (sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) has shown activity in animal models for tendon healing, ligament repair, gut protection (NSAIDs, alcohol damage), and wound healing
- It appears to upregulate growth factor expression (VEGF, FGF) and modulate the nitric oxide system
- Despite extensive preclinical literature, no completed human randomized controlled trials exist as of 2026, and its regulatory status varies by jurisdiction
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