nounIntermediate
Definition
Collagen that has been enzymatically broken into small peptide fragments (2–3 kDa), making it water-soluble at any temperature and approximately 90% bioavailable after oral ingestion.

Detailed Explanation

Collagen that has been enzymatically broken into small peptide fragments (2–3 kDa), making it water-soluble at any temperature and approximately 90% bioavailable after oral ingestion. Synonymous with collagen peptides. The hydrolysis process uses food-grade proteases (typically from Bacillus species or papain) to cleave the collagen triple helix into fragments rich in Gly-Pro-Hyp and related tripeptide sequences. These fragments are absorbed as di- and tripeptides via the PepT1 intestinal transporter.

Key Facts

  • Collagen that has been enzymatically broken into small peptide fragments (2–3 kDa), making it water-soluble at any temperature and approximately 90% bioavailable after oral ingestion.
  • Synonymous with collagen peptides.
  • The hydrolysis process uses food-grade proteases (typically from Bacillus species or papain) to cleave the collagen triple helix into fragments rich in Gly-Pro-Hyp and related tripeptide sequences.
  • These fragments are absorbed as di- and tripeptides via the PepT1 intestinal transporter.
Related Terms Collagen Peptides Collagen Gelatin Hydrolysis

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