nounIntermediate
Definition
Freeze-drying process used to preserve peptides in a stable, dry powder form.
Detailed Explanation
Freeze-drying process used to preserve peptides in a stable, dry powder form. The peptide solution is frozen and then subjected to vacuum, causing ice to sublimate directly to vapor without passing through a liquid phase. The result is a porous 'cake' that can be stored for months to years at –20°C to room temperature (depending on the peptide). Reconstitution with sterile water or bacteriostatic water restores the peptide solution. Lyophilization is the standard commercial format for research, compounding, and pharmaceutical peptides.
Key Facts
- Freeze-drying process used to preserve peptides in a stable, dry powder form.
- The peptide solution is frozen and then subjected to vacuum, causing ice to sublimate directly to vapor without passing through a liquid phase.
- The result is a porous 'cake' that can be stored for months to years at –20°C to room temperature (depending on the peptide).
- Reconstitution with sterile water or bacteriostatic water restores the peptide solution.
- Lyophilization is the standard commercial format for research, compounding, and pharmaceutical peptides.
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