nounIntermediate
Definition
Copper-binding tripeptide (glycine-histidine-lysine with Cu²⁺) naturally present in human plasma, saliva, and urine.

Detailed Explanation

Copper-binding tripeptide (glycine-histidine-lysine with Cu²⁺) naturally present in human plasma, saliva, and urine. Plasma levels decline from ~200 ng/mL at age 20 to ~80 ng/mL by age 60. GHK-Cu promotes wound healing, collagen synthesis, glycosaminoglycan production, and angiogenesis. It also has anti-inflammatory and antioxidant properties. Used in topical skincare products and studied for hair growth, tissue remodeling, and post-surgical healing. The copper ion is essential for activity.

Key Facts

  • Copper-binding tripeptide (glycine-histidine-lysine with Cu²⁺) naturally present in human plasma, saliva, and urine.
  • Plasma levels decline from ~200 ng/mL at age 20 to ~80 ng/mL by age 60.
  • GHK-Cu promotes wound healing, collagen synthesis, glycosaminoglycan production, and angiogenesis.
  • It also has anti-inflammatory and antioxidant properties.
  • Used in topical skincare products and studied for hair growth, tissue remodeling, and post-surgical healing.
Related Terms Tripeptide Collagen Matrikine Bioactive Peptide

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