Definition
A peptide with exactly 4 amino acid residues joined by 3 peptide bonds.

Detailed Explanation

A peptide with exactly 4 amino acid residues joined by 3 peptide bonds. Notable tetrapeptides include tuftsin (Thr-Lys-Pro-Arg), a natural immunostimulatory peptide from IgG that enhances phagocytosis; FMRF-amide (Phe-Met-Arg-Phe-NH₂), a neuropeptide found in invertebrates that regulates muscle contraction; Ac-SDKP (N-acetyl-Ser-Asp-Lys-Pro), a fragment of thymosin beta-4 with anti-fibrotic properties regulated by ACE; and rigin (Gly-Gln-Pro-Arg), studied for anti-inflammatory activity. In cosmetics, tetrapeptides like Matrixyl (palmitoyl-GQPR) are used in anti-aging products, with claims of stimulating collagen production in skin.

Key Facts

  • A peptide with exactly 4 amino acid residues joined by 3 peptide bonds.
  • Notable tetrapeptides include tuftsin (Thr-Lys-Pro-Arg), a natural immunostimulatory peptide from IgG that enhances phagocytosis; FMRF-amide (Phe-Met-Arg-Phe-NH₂), a neuropeptide found in invertebrates that regulates muscle contraction; Ac-SDKP (N-acetyl-Ser-Asp-Lys-Pro), a fragment of thymosin beta-4 with anti-fibrotic properties regulated by ACE; and rigin (Gly-Gln-Pro-Arg), studied for anti-inflammatory activity.
  • In cosmetics, tetrapeptides like Matrixyl (palmitoyl-GQPR) are used in anti-aging products, with claims of stimulating collagen production in skin.
Related Terms Tripeptide Pentapeptide Dipeptide Oligopeptide Peptide

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